Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7029792 | 0.95 | CCR4 (0.66) | CCR4 | |
| SCHEMBL1733189 | 0.88 | CCR4 (0.75) | CCR4 | |
| SCHEMBL1731477 | 0.85 | CCR4 (0.73) | CCR4 | |
| SCHEMBL6847968 | 0.84 | CCR4 (0.69) | CCR4 | |
| SCHEMBL1732817 | 0.82 | CCR4 (0.79) | CCR4 | |
| SCHEMBL1732728 | 0.80 | CCR4 (1.00) | CCR4 | |
| SCHEMBL12282384 | 0.80 | CCR4 (0.76) | CCR4 | |
| SCHEMBL1733170 | 0.79 | CCR4 (0.76) | CCR4 | |
| SCHEMBL1733375 | 0.79 | CCR4 (0.76) | CCR4 | |
| SCHEMBL1733262 | 0.78 | CCR4 (0.73) | CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1467976-A1 | N-PYRAZINYL-PHENYLSULPHONAMIDES AND THEIR USE IN THE TREATMENT OF CHEMOKINE MEDIATED DISEASES | AstraZeneca AB (SE) | 2004-10-20 | — | — | EP | disclosed |
| WO-2003059893-A1 | N-PYRAZINYL-PHENYLSULPHONAMIDES AND THEIR USE IN THE TREATMENT OF CHEMOKINE MEDIATED DISEASES | ASTRAZENECA AB (SE) | 2003-07-24 | — | — | WO | disclosed |