SCHEMBL7030619

SCHEMBL7030619

COC(=O)c1cccc(-c2ccccc2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]2O)c1

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23480033 1.00 TYR (0.58) TYR
SCHEMBL7030610 1.00 TYR (0.58) TYR
SCHEMBL23479694 1.00 TYR (0.58) TYR
SCHEMBL23479673 1.00 TYR (0.58) TYR
SCHEMBL23457411 0.88 TYR (0.54) TYR
SCHEMBL26356540 0.88 TYR (0.54) TYR
SCHEMBL23479715 0.88 TYR (0.54) TYR
SCHEMBL23480061 0.88 TYR (0.54) TYR
SCHEMBL23479732 0.88
SCHEMBL23457448 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0758243-B1 BINDING OF E-SELECTIN, P-SELECTIN OR L-SELECTIN TO SIALYL-LEWISx OR SIALYL-LEWISa TEXAS BIOTECHNOLOGY CORP (US) 2003-03-12 EP disclosed
EP-0758243-A4 BINDING OF E-SELECTIN, P-SELECTIN OR L-SELECTIN TO SIALYL-LEWISx OR SIALYL-LEWISa TEXAS BIOTECHNOLOGY CORP (US) 1997-08-20 EP disclosed
EP-0758243-A1 BINDING OF E-SELECTIN, P-SELECTIN OR L-SELECTIN TO SIALYL-LEWISx OR SIALYL-LEWISa TEXAS BIOTECHNOLOGY CORPORATION (US) 1997-02-19 EP disclosed
WO-1995029682-A1 BINDING OF E-SELECTIN, P-SELECTIN OR L-SELECTIN TO SIALYL-LEWISx OR SIALYL-LEWIS?a¿ TEXAS BIOTECHNOLOGY CORPORATION (US) 1995-11-09 WO disclosed
US-5444050-A Binding of E-selectin or P-selectin to sialyl Lewisx or sialyl-Lewisa TEXAS BIOTECHNOLOGY CORPORATION (US) 1995-08-22 US disclosed