Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 3/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2210682 | 0.89 | GRIN2D (0.52) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL7146424 | 0.87 | GRIN2D (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Acetic Acid SCHEMBL4360281 | 0.86 | EPHX2 (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL17837966 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL13387068 | 0.75 | — | — | |
| Acetic Acid SCHEMBL2805454 | 0.73 | EPHX2 (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL13157704 | 0.69 | GRIN2D (0.48) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Amantadine SCHEMBL7705557 | 0.69 | GRIN1 (0.72) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6868049 | 0.67 | GRIN2D (0.52) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL11148894 | 0.66 | GRIN2D (0.58) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082329-B1 | PLATINUM COMPLEX, ITS PREPARATION AND THERAPEUTIC APPLICATION | PLIVA LACHEMA AS (CZ) | 2003-03-05 | — | — | EP | disclosed |
| US-6503943-B1 | Platinum complex, its preparation and therapeutic application | PLIVA-LACHEMA, A.S. (CZ) | 2003-01-07 | — | — | US | disclosed |
| EP-1082330-B1 | PLATINUM COMPLEX, ITS PREPARATION AND THERAPEUTIC APPLICATION | PLIVA LACHEMA AS (CZ) | 2002-04-03 | — | — | EP | disclosed |
| EP-1082330-A1 | PLATINUM COMPLEX, ITS PREPARATION AND THERAPEUTIC APPLICATION | Pliva-Lachema A.S. (CZ) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999061451-A1 | PLATINUM COMPLEX, ITS PREPARATION AND THERAPEUTIC APPLICATION | PLIVA-LACHEMA A.S. (CZ) | 1999-12-02 | — | — | WO | disclosed |