Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7030104 | 0.90 | CYP2C9 (0.39) | ESR2CYP2C9 | |
| SCHEMBL7022894 | 0.90 | FFAR4 (0.34) | ESR2CYP2C9 | |
| SCHEMBL7020366 | 0.89 | ESR2 (0.31) | ESR2ESR1CYP3A4CYP2C9 | |
| SCHEMBL7024993 | 0.88 | ESR2 (0.33) | ESR2 | |
| SCHEMBL7031024 | 0.88 | ESR2 (0.35) | ESR2ESR1CYP3A4CYP2C9 | |
| SCHEMBL7026846 | 0.87 | CYP2C9 (0.33) | ESR2CYP2C9 | |
| SCHEMBL8732098 | 0.83 | ESR2 (0.38) | ESR2ESR1CYP3A4CYP2C9 | |
| SCHEMBL8731049 | 0.83 | ESR2 (0.38) | ESR2ESR1CYP3A4CYP2C9 | |
| SCHEMBL8731057 | 0.83 | ESR2 (0.38) | ESR2ESR1CYP3A4CYP2C9 | |
| SCHEMBL7031028 | 0.82 | ESR2 (0.41) | ESR2ESR1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754668-B1 | Fluorobenzylether derivatives | ROLIC AG (CH) | 2003-02-05 | — | — | EP | disclosed |
| EP-0754668-A2 | Fluorobenzylether derivatives | Rolic AG (CH) | 1997-01-22 | — | — | EP | disclosed |