Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 4/20 | 0.34 |
| ▸ | CTSS | P25774 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL385838 | 0.85 | MEN1 (0.47) | CYP2D6MEN1GAAKMT2ATDP1 | |
| SCHEMBL3363685 | 0.85 | MEN1 (0.47) | CYP2D6MEN1GAAKMT2ATDP1 | |
| SCHEMBL735620 | 0.85 | MEN1 (0.47) | CYP2D6MEN1GAAKMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL15136639 | 0.83 | MEN1 (0.46) | CYP2D6MEN1GAAKMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL15649122 | 0.83 | MEN1 (0.46) | CYP2D6MEN1GAAKMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL17389225 | 0.83 | MEN1 (0.46) | CYP2D6MEN1GAAKMT2ATDP1 | |
| SCHEMBL8362351 | 0.74 | MEN1 (0.41) | CYP2D6MEN1GAAKMT2ATDP1 | |
| Butylamine SCHEMBL28495559 | 0.73 | MEN1 (0.41) | MEN1GAAKMT2ATDP1CA1 | |
| SCHEMBL2748354 | 0.72 | MEN1 (0.49) | MEN1GAAKMT2ATDP1CA1 | |
| SCHEMBL2723370 | 0.71 | CA1 (0.46) | CYP2D6MEN1GAAKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8126554-B2 | Implantable medical device with chemical sensor and related methods | CARDIAC PACEMAKERS, INC. (US) | 2012-02-28 | — | — | US | disclosed |