SCHEMBL7032792

SCHEMBL7032792

CCOC(=O)C(C)=Cc1cc(F)c(Oc2ccc(S(=O)(=O)NCCN(C)C)cc2)c(F)c1

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SLC9A3 P48764 14/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13276136 0.92 SLC9A3 (0.57) SLC9A3
SCHEMBL13276135 0.92 SLC9A3 (0.57) SLC9A3
SCHEMBL24380143 0.89 SLC9A3 (0.54) SLC9A3
SCHEMBL13449814 0.89 SLC9A3 (0.69) SLC9A3
SCHEMBL13449818 0.89 SLC9A3 (0.69) SLC9A3
SCHEMBL13467435 0.87 SLC9A3 (0.67) SLC9A3
SCHEMBL13466643 0.87 SLC9A3 (0.67) SLC9A3
SCHEMBL13286048 0.86 SLC9A3 (0.53) SLC9A3
SCHEMBL16479090 0.86 SLC9A3 (0.66) SLC9A3
SCHEMBL16638603 0.86 SLC9A3 (0.51) SLC9A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1322602-A1 SUBSTITUTED CINNAMIC ACID GUANIDIDES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AS A MEDICAMENT, AND TO A MEDICAMENT CONTAINING THESE COMPOUNDS Aventis Pharma Deutschland GmbH (DE) 2003-07-02 — — EP disclosed
US-6399824-B1 FOR THERAPY AND PROPHYLAXIS OF ARRHYTHMIAS, CARDIAC INFRACTION, ISCHEMIC CONDITIONS, ANGINA PECTORIS, SHOCK, FOR PRESERVING AND STORING A TRANSPLANT FOR SURGICAL MEASURE AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2002-06-04 — — US disclosed
US-20020058710-A1 SUBSTITUTED CINNAMIC, ACID GUANIDIDES, PROCESS FOR THEIR PREPARATION, THEIR USE AS A MEDICAMENT, AND MEDICAMENT COMPRISING THEM AVENTIS PHARMA DEUTSCHLAND GMBH. 2002-05-16 — — US disclosed
WO-2002024637-A1 SUBSTITUTED CINNAMIC ACID GUANIDIDES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AS A MEDICAMENT, AND TO A MEDICAMENT CONTAINING THESE COMPOUNDS AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2002-03-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020058710-A1 SUBSTITUTED CINNAMIC, ACID GUANIDIDES, PROCESS FOR THEIR PREPARATION, THEIR USE AS A MEDICAMENT, AND MEDICAMENT COMPRISING THEM GANC, GMPS, GCDH SLC9A3 4133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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