Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.51 |
| ▸ | TPMT | P51580 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6725300 | 0.75 | PPARG (0.43) | SRD5A2TPMTCES2CES1MEN1 | |
| SCHEMBL6720828 | 0.73 | TPMT (0.40) | TPMTDAOTSHRNAPRTGRIN2D | |
| SCHEMBL6725924 | 0.73 | TPMT (0.40) | TPMTTSHRMEN1KMT2ATDP1 | |
| SCHEMBL9005549 | 0.72 | SRD5A2 (0.63) | SRD5A2CES2CES1KMT2AAKR1C3 | |
| SCHEMBL7498991 | 0.72 | SRD5A2 (0.90) | SRD5A2ESR1ESR2DAOTSHR | |
| SCHEMBL14024230 | 0.70 | TPMT (0.81) | TPMT | |
| SCHEMBL19379565 | 0.70 | PPARA (0.51) | PPARA | |
| SCHEMBL4269670 | 0.70 | MEN1 (0.63) | SRD5A2TPMTTSHRMEN1KMT2A | |
| SCHEMBL17854065 | 0.69 | TPMT (0.58) | TPMTTSHRTDP1TTR | |
| SCHEMBL26828022 | 0.68 | TPMT (0.52) | TPMTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6638977-B1 | Biaryl and benzyl ethers and thioethers | CORVAS INTERNATIONAL, INC. | 2003-10-28 | — | — | US | claimed |