Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.62 |
| ▸ | GANAB | Q14697 | 1/20 | 0.62 |
| ▸ | GLB1 | P16278 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | AGL | P35573 | 2/20 | 0.45 |
| ▸ | PYGL | P06737 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.43 |
| ▸ | MAN2B2 | Q9Y2E5 | 1/20 | 0.43 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19328384 | 1.00 | GBA1 (0.62) | GBA1GANABGLB1MGAMGAA | |
| SCHEMBL2434766 | 1.00 | GBA1 (0.62) | GBA1GANABGLB1MGAMGAA | |
| SCHEMBL9495785 | 1.00 | GBA1 (0.62) | GBA1GANABGLB1MGAMGAA | |
| SCHEMBL612200 | 1.00 | GBA1 (0.62) | GBA1GANABGLB1MGAMGAA | |
| SCHEMBL14246910 | 1.00 | GBA1 (0.62) | GBA1GANABGLB1MGAMGAA | |
| SCHEMBL23531404 | 1.00 | GBA1 (0.62) | GBA1GANABGLB1MGAMGAA | |
| SCHEMBL2265142 | 1.00 | GBA1 (0.62) | GBA1GANABGLB1MGAMGAA | |
| Hydrochloric Acid SCHEMBL9496174 | 0.98 | GBA1 (0.60) | GBA1GANABGLB1MGAMGAA | |
| Hydrochloric Acid SCHEMBL9497390 | 0.98 | GBA1 (0.60) | GBA1GANABGLB1MGAMGAA | |
| Hydrochloric Acid SCHEMBL960466 | 0.98 | GBA1 (0.60) | GBA1GANABGLB1MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375651-B1 | Novel glycosidase inhibitors | MONSANTO CO (US) | 1994-10-05 | — | — | EP | claimed |
| EP-0375651-A1 | Novel glycosidase inhibitors | MONSANTO COMPANY (US) | 1990-06-27 | — | — | EP | claimed |
| US-4894388-A | 1,4-DIDEOXY-1,4-IMINO-L-ALLITOL | MONSANTO COMPANY (US) | 1990-01-16 | — | — | US | claimed |
| JP-2212470-A | — | — | None | — | — | JP | disclosed |
| EP-0749423-B1 | PIPERIDINES AND PYRROLIDINES | NOVO NORDISK AS (DK) | 2003-06-18 | — | — | EP | disclosed |
| EP-0858335-B1 | 2-ALKYLPYRROLIDINES | NOVO NORDISK AS (DK) | 2003-03-12 | — | — | EP | disclosed |
| US-6451836-B1 | Method of inhibiting liver glycogen phosphorylase with 2-alkylpyrrolidines | NOVO NORDISK A/S (DK) | 2002-09-17 | — | — | US | disclosed |
| EP-1040827-A2 | Use of 2-alkylpyrrolidines for the treatment of diabetes | NOVO NORDISK A/S (DK) | 2000-10-04 | — | — | EP | disclosed |
| US-5863903-A | ANTIDIABETIC AGENT | NOVO NORDISK A/S (DK) | 1999-01-26 | — | — | US | disclosed |
| US-5854272-A | 2-alkylpyrrolidines | NOVO NORDISK A/S (DK) | 1998-12-29 | — | — | US | disclosed |
| EP-0884050-A1 | Use of 3,4-dihydroxy-2-hydroxymethylpyrrolidine for the treatment of diabetes | NOVO NORDISK A/S (DK) | 1998-12-16 | — | — | EP | disclosed |
| EP-0375651-B1 | Novel glycosidase inhibitors | MONSANTO CO (US) | 1994-10-05 | — | — | EP | disclosed |
| US-5026870-A | Method of preparing bicyclic tetrahydroxylated pyrrolizidines | MONSANTO COMPANY (US) | 1991-06-25 | — | — | US | disclosed |
| US-5025098-A | Method of preparing bicyclic tetrahydroxylated pyrrolizidines | MONSANTO COMPANY (US) | 1991-06-18 | — | — | US | disclosed |
| EP-0417059-A2 | Bicyclic tetrahydroxylated pyrrolizidines | MONSANTO COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| US-4992460-A | Bicyclic tetrahydroxylated pyrrolizidines | MONSANTO COMPANY (US) | 1991-02-12 | — | — | US | disclosed |
| JP-H02212470-A | NOVEL GLYCOSIDASE INHIBITOR | MONSANTO CO | 1990-08-23 | — | — | JP | disclosed |
| EP-0375651-A1 | Novel glycosidase inhibitors | MONSANTO COMPANY (US) | 1990-06-27 | — | — | EP | disclosed |
| US-4894388-A | 1,4-DIDEOXY-1,4-IMINO-L-ALLITOL | MONSANTO COMPANY (US) | 1990-01-16 | — | — | US | disclosed |
| US-4894388-A | 1,4-DIDEOXY-1,4-IMINO-L-ALLITOL | MONSANTO COMPANY (US) | 1990-01-16 | — | — | US | disclosed |