Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.31 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8390420 | 0.93 | KDM5A (0.33) | KDM5AKDM4CKDM5BRORCESR2 | |
| SCHEMBL7034715 | 0.93 | KDM5A (0.33) | KDM5AKDM4CKDM5BRORCESR2 | |
| SCHEMBL7026842 | 0.89 | KDM5A (0.34) | KDM5AKDM4CKDM5BRORCESR2 | |
| SCHEMBL8725555 | 0.88 | ESR2 (0.33) | ESR2 | |
| SCHEMBL7024827 | 0.86 | CYP2C9 (0.34) | KDM5AKDM4CKDM5BRORCSGPL1 | |
| SCHEMBL8387101 | 0.86 | CYP2C9 (0.34) | KDM5AKDM4CKDM5BRORCSGPL1 | |
| SCHEMBL8389637 | 0.85 | CYP2C9 (0.34) | KDM5AKDM4CKDM5BRORCSGPL1 | |
| SCHEMBL7033190 | 0.85 | CYP2C9 (0.34) | KDM5AKDM4CKDM5BRORCSGPL1 | |
| SCHEMBL8387212 | 0.85 | — | — | |
| SCHEMBL7106101 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754668-B1 | Fluorobenzylether derivatives | ROLIC AG (CH) | 2003-02-05 | — | — | EP | disclosed |
| EP-0754668-A2 | Fluorobenzylether derivatives | Rolic AG (CH) | 1997-01-22 | — | — | EP | disclosed |