Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 4/20 | 0.48 |
| ▸ | HKDC1 | Q2TB90 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | TNNI3 | P19429 | 2/20 | 0.48 |
| ▸ | TNNT2 | P45379 | 2/20 | 0.48 |
| ▸ | TNNC1 | P63316 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7036101 | 1.00 | TYR (0.49) | TYRUSP2HKDC1L3MBTL1TNNI3 | |
| SCHEMBL29193245 | 0.91 | TYR (0.56) | TYRUSP2HKDC1L3MBTL1TNNI3 | |
| SCHEMBL17653886 | 0.91 | TYR (0.56) | TYRUSP2HKDC1L3MBTL1TNNI3 | |
| SCHEMBL14120361 | 0.91 | TYR (0.56) | TYRUSP2HKDC1L3MBTL1TNNI3 | |
| SCHEMBL7028773 | 0.86 | SLC5A2 (0.54) | TYRNPC1RAB9ASLC5A2SLC5A1 | |
| SCHEMBL7028761 | 0.86 | SLC5A2 (0.54) | TYRNPC1RAB9ASLC5A2SLC5A1 | |
| SCHEMBL14120495 | 0.84 | SELP (0.62) | TYRNPC1RAB9AKDM4EMAPT | |
| SCHEMBL14120492 | 0.84 | SELP (0.62) | TYRNPC1RAB9AKDM4EMAPT | |
| SCHEMBL7033574 | 0.83 | SLC5A2 (0.56) | TYRNPC1RAB9ASLC5A2SLC5A1 | |
| SCHEMBL7038463 | 0.83 | SLC28A3 (0.47) | TYRNPC1RAB9ASLC5A2SLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758243-B1 | BINDING OF E-SELECTIN, P-SELECTIN OR L-SELECTIN TO SIALYL-LEWISx OR SIALYL-LEWISa | TEXAS BIOTECHNOLOGY CORP (US) | 2003-03-12 | — | — | EP | disclosed |
| EP-0758243-A4 | BINDING OF E-SELECTIN, P-SELECTIN OR L-SELECTIN TO SIALYL-LEWISx OR SIALYL-LEWISa | TEXAS BIOTECHNOLOGY CORP (US) | 1997-08-20 | — | — | EP | disclosed |
| EP-0758243-A1 | BINDING OF E-SELECTIN, P-SELECTIN OR L-SELECTIN TO SIALYL-LEWISx OR SIALYL-LEWISa | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995029682-A1 | BINDING OF E-SELECTIN, P-SELECTIN OR L-SELECTIN TO SIALYL-LEWISx OR SIALYL-LEWIS?a¿ | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1995-11-09 | — | — | WO | disclosed |