Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1R | P00736 | 15/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4259213 | 0.90 | C1R (0.46) | C1RMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL4259369 | 0.87 | C1R (0.48) | C1RMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL4268147 | 0.79 | C1R (0.47) | C1RMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL4262925 | 0.79 | ELANE (0.49) | C1RMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL4264585 | 0.78 | C1R (0.47) | C1RMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL4264396 | 0.78 | C1R (0.46) | C1RMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL7033542 | 0.78 | C1R (0.34) | C1R | |
| SCHEMBL4259210 | 0.78 | MAPT (0.46) | C1RMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL4263346 | 0.77 | C1R (0.43) | C1RMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL4260532 | 0.76 | C1R (0.43) | C1RMAPTALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446125-A1 | THIENO-(1,3)-OXAZIN-4-ONES WITH LIPASE INHIBITING ACTIVITY | Alizyme Therapeutics Limited (GB) | 2004-08-18 | — | — | EP | claimed |
| WO-2003020282-A1 | THIENO-(1,3)-OXAZIN-4-ONES WITH LIPASE INHIBITING ACTIVITY | ALIZYME THERAPEUTICS LIMITED (GB) | 2003-03-13 | — | — | WO | claimed |