Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.78 |
| ▸ | PPARA | Q07869 | 4/20 | 0.78 |
| ▸ | SERPINE1 | P05121 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | WDR5 | P61964 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7041821 | 0.99 | PPARG (0.80) | PPARGPPARASERPINE1TP53WDR5 | |
| Lithium Ion SCHEMBL7035485 | 0.88 | PPARG (1.00) | PPARGPPARATP53WDR5CYP1A2 | |
| SCHEMBL7040714 | 0.87 | PPARG (0.76) | PPARGPPARATP53WDR5MEN1 | |
| SCHEMBL7038130 | 0.82 | SERPINE1 (0.70) | PPARGPPARASERPINE1TP53MEN1 | |
| SCHEMBL7040866 | 0.81 | PPARG (0.67) | PPARGPPARASERPINE1TP53AKR1C4 | |
| SCHEMBL1307242 | 0.80 | PPARG (0.81) | PPARGPPARASERPINE1TP53AKR1C4 | |
| SCHEMBL7040843 | 0.80 | PPARG (0.69) | PPARGPPARASERPINE1TP53AKR1C4 | |
| SCHEMBL7038137 | 0.80 | PPARG (0.68) | PPARGPPARASERPINE1TP53AKR1C4 | |
| SCHEMBL7037662 | 0.80 | PPARG (0.56) | PPARGPPARASERPINE1TP53HDAC2 | |
| SCHEMBL7038105 | 0.78 | PPARG (0.62) | PPARGPPARASERPINE1TP53AKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030073862-A1 | Compounds | BIOVITRUM AB (SE) | 2003-04-17 | — | — | US | disclosed |
| WO-2003004458-A1 | NEW COMPOUNDS | BIOVITRUM AB (SE) | 2003-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073862-A1 | Compounds | PPARG, PPARA, PPARD | PPARG 1/4885PPARA 2/4885SERPINE1 1107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.