Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CXCR4 | P61073 | 8/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23428518 | 0.85 | CXCR4 (0.63) | TSHRCXCR4CHRM2CHRM4CHRM5 | |
| SCHEMBL5556094 | 0.85 | TSHR (0.50) | TSHRMAPTSMN1; SMN2LIN28ATDP1 | |
| SCHEMBL12089127 | 0.82 | TDP1 (0.55) | TSHRMAPTSMN1; SMN2LIN28ATDP1 | |
| SCHEMBL15883099 | 0.81 | TSHR (0.53) | TSHRSMN1; SMN2CHRM2CHRM4CHRM5 | |
| SCHEMBL17799257 | 0.80 | CXCR4 (0.41) | TSHRCXCR4CHRM2CHRM4CHRM5 | |
| SCHEMBL20851244 | 0.80 | CXCR4 (0.44) | TSHRCXCR4CHRM2CHRM4CHRM5 | |
| SCHEMBL7093038 | 0.79 | TDP1 (0.52) | TSHRMAPTSMN1; SMN2LIN28ATDP1 | |
| SCHEMBL18997830 | 0.79 | TSHR (0.56) | TSHRSMN1; SMN2CXCR4CHRM2CHRM4 | |
| SCHEMBL22894684 | 0.78 | CXCR4 (0.56) | TSHRMAPTSMN1; SMN2LIN28ATDP1 | |
| SCHEMBL172599 | 0.78 | TDP1 (0.50) | TSHRMAPTSMN1; SMN2LIN28ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1285055-A1 | TARGETED MOIETIES FOR USE IN BLEACH CATALYSTS | UNILEVER PLC (GB) | 2003-02-26 | — | — | EP | disclosed |
| WO-2001092455-A1 | TARGETED MOIETIES FOR USE IN BLEACH CATALYSTS | UNILEVER PLC (GB) | 2001-12-06 | — | — | WO | disclosed |
| WO-2001064825-A1 | BLEACHING COMPOSITION AND METHOD FOR BLEACHING LAUNDRY FABRICS | UNILEVER PLC (GB) | 2001-09-07 | — | — | WO | disclosed |