Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | BUB1 | O43683 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20973202 | 0.85 | CHRM2 (0.44) | CHRM2CHRM1CHRM3NR1H2EPHX2 | |
| SCHEMBL21274860 | 0.85 | CHRM2 (0.44) | CHRM2CHRM1CHRM3NR1H2EPHX2 | |
| SCHEMBL2432633 | 0.82 | NR1H2 (0.36) | CHRM2CHRM1CHRM3NR1H2EPHX2 | |
| SCHEMBL142226 | 0.81 | CHRM2 (0.41) | CHRM2CHRM1CHRM3NR1H2EPHX2 | |
| SCHEMBL4769152 | 0.81 | CHRM2 (0.41) | CHRM2CHRM1CHRM3NR1H2EPHX2 | |
| SCHEMBL6491588 | 0.81 | CHRM2 (0.41) | CHRM2CHRM1CHRM3NR1H2EPHX2 | |
| SCHEMBL5153017 | 0.81 | CHRM2 (0.41) | CHRM2CHRM1CHRM3NR1H2EPHX2 | |
| SCHEMBL1924787 | 0.81 | CHRM2 (0.41) | CHRM2CHRM1CHRM3NR1H2EPHX2 | |
| SCHEMBL3679572 | 0.81 | CHRM2 (0.41) | CHRM2CHRM1CHRM3NR1H2EPHX2 | |
| SCHEMBL5203966 | 0.81 | CHRM2 (0.41) | CHRM2CHRM1CHRM3NR1H2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0989135-B1 | NOVEL PHOSPHINOPYRROLIDINE COMPOUNDS AND PROCESS FOR PRODUCING THE SAME | DAIICHI FINE CHEM CO LTD (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-6229019-B1 | Phosphinopyrroline compounds and process for producing the same | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2001-05-08 | — | — | US | disclosed |