⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3106051 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL28751463 | 0.76 | — | — | |
| SCHEMBL2876989 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL27553615 | 0.72 | — | — | |
| SCHEMBL1008670 | 0.68 | — | — | |
| SCHEMBL919473 | 0.68 | — | — | |
| SCHEMBL7176405 | 0.68 | — | — | |
| Water SCHEMBL919928 | 0.66 | TSHR (0.32) | — | |
| Bromide SCHEMBL5087860 | 0.66 | TSHR (0.32) | — | |
| Iodide SCHEMBL5088516 | 0.66 | TSHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6599558-B1 | Covalently bonding vinylalkoxysilane and graft polymerizing with further monomers forming hydrophilic layer; inhibiting restenosis and thrombosis | POLYBIOMED LIMITED (GB) | 2003-07-29 | — | — | US | disclosed |
| EP-0988071-B1 | TREATING METAL SURFACES TO ENHANCE BIO-COMPATIBILITY AND/OR PHYSICAL CHARACTERISTICS | POLYBIOMED LTD (GB) | 2003-02-26 | — | — | EP | disclosed |
| EP-0988071-A2 | TREATING METAL SURFACES TO ENHANCE BIO-COMPATIBILITY AND/OR PHYSICAL CHARACTERISTICS | PolyBioMed Limited (GB) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998055162-A2 | TREATING METAL SURFACES TO ENHANCE BIO-COMPATIBILITY | POLYBIOMED LIMITED (GB) | 1998-12-10 | — | — | WO | disclosed |
| US-5356433-A | Using an amino containing organosilane compound | CORDIS CORPORATION (US) | 1994-10-18 | — | — | US | disclosed |