Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.60 |
| ▸ | COMT | P21964 | 1/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.50 |
| ▸ | UQCRB | P14927 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7040443 | 0.88 | MEN1 (0.66) | KDM4EPDE4DL3MBTL1NPC1RAB9A | |
| SCHEMBL16525559 | 0.85 | PDE4D (0.66) | KDM4EPDE4DCOMTL3MBTL1NPC1 | |
| SCHEMBL13656151 | 0.81 | PDE4D (0.59) | KDM4EPDE4DCOMTL3MBTL1NPC1 | |
| SCHEMBL30132520 | 0.81 | KMT2A (0.60) | TLR7MEN1PABPC1KMT2AEIF4H | |
| SCHEMBL20554412 | 0.81 | KMT2A (0.60) | TLR7MEN1PABPC1KMT2AEIF4H | |
| SCHEMBL16525522 | 0.81 | KDR (0.65) | KDM4EPDE4DBRD4NPC1RAB9A | |
| SCHEMBL6332102 | 0.80 | PDE4D (0.58) | KDM4EPDE4DCOMTL3MBTL1NPC1 | |
| SCHEMBL20554437 | 0.79 | BRD4 (0.47) | KDM4EBRD4TLR7L3MBTL1MEN1 | |
| SCHEMBL20554224 | 0.79 | ELANE (0.53) | TLR7L3MBTL1MEN1PABPC1KMT2A | |
| SCHEMBL30132571 | 0.79 | ELANE (0.53) | TLR7L3MBTL1MEN1PABPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003055477-A1 | METHOD FOR THE TREATMENT OF MC RECEPTOR RELATED DISORDERS WITH A CHELATE AND/OR A CHELATOR | 7TM PHARMA A/S (DK) | 2003-07-10 | — | — | WO | disclosed |
| WO-2003003009-A1 | USE OF METAL-ION CHELATES IN VALIDATING BIOLOGICAL MOLECULES AS DRUG TARGETS IN TEST ANIMAL MODELS | 7TM PHARMA A/S (DK) | 2003-01-09 | — | — | WO | disclosed |
| WO-2003003008-A1 | CHEMICAL LIBRARIES USEFUL FOR DRUG DISCOVERY PROCESSES | 7TM PHARMA A/S (DK) | 2003-01-09 | — | — | WO | disclosed |