Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1485069 | 0.82 | CYP3A4 (0.56) | CYP1A2CYP3A4CYP2C9CYP2C19GPR119 | |
| SCHEMBL16944266 | 0.82 | POLB (0.42) | CYP1A2CYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL7036622 | 0.79 | CYP1A2 (0.54) | CYP1A2CYP3A4CYP2C9CYP2C19GPR119 | |
| SCHEMBL14862815 | 0.79 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2C9CYP2C19GPR119 | |
| SCHEMBL2658961 | 0.79 | CYP1A2 (0.54) | CYP1A2CYP3A4CYP2C9CYP2C19GPR119 | |
| SCHEMBL2896197 | 0.79 | CYP1A2 (0.54) | CYP1A2CYP3A4CYP2C9CYP2C19GPR119 | |
| SCHEMBL4447504 | 0.79 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2C9CYP2C19GPR119 | |
| SCHEMBL12391462 | 0.79 | BLM (0.43) | CYP1A2CYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL20201227 | 0.79 | HSD17B10 (0.42) | CYP1A2CYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL21021768 | 0.78 | POLB (0.40) | CYP1A2CYP3A4CYP2C9CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9629369-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2017-04-25 | — | — | US | disclosed |
| WO-2015112739-A9 | COMPOUNDS AND METHOD FOR TREATING PARP1-DEFICIENT CANCERS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2016-10-20 | — | — | WO | disclosed |
| WO-2015112739-A1 | COMPOUNDS AND METHOD FOR TREATING PARP1-DEFICIENT CANCERS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2015-07-30 | — | — | WO | disclosed |
| US-6613747-B2 | Erythromycins to treat community-acquired pneumonia and upper and lower respiratory tract, skin and soft tissue, hospital-acquired lung, bone and joint infections; Staphyloccus; Enterococcus; Moraxella; Hemophilus; antibiotic resistance | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2003-09-02 | — | — | US | disclosed |
| US-20030013663-A1 | 6-O-CARBAMOYL KETOLIDE ANTIBACTERIALS | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2003-01-16 | — | — | US | disclosed |
| US-6472372-B1 | 6-O-Carbamoyl ketolide antibacterials | ORTHO-MCNEIL PHARMACEUTICALS, INC. | 2002-10-29 | — | — | US | disclosed |
| US-20020115620-A1 | 6-0-carbamoyl ketolide antibacterials | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2002-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013663-A1 | 6-O-CARBAMOYL KETOLIDE ANTIBACTERIALS | Q6ZSR9, KDM4E, HK1 | CYP1A2 2899/4885CYP3A4 1070/4885CYP2C9 747/4885 |
| US-20020115620-A1 | 6-0-carbamoyl ketolide antibacterials | Q6ZSR9, HK1, KDM4E | CYP1A2 3028/4885CYP3A4 1193/4885CYP2C9 753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.