Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 16/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9236113 | 0.86 | ADRB3 (0.57) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7041424 | 0.86 | ADRB3 (0.57) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7044158 | 0.86 | ADRB3 (0.57) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7039828 | 0.76 | ADRB3 (0.71) | ADRB3 | |
| SCHEMBL7042543 | 0.74 | ADRB3 (0.60) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7042548 | 0.74 | ADRB3 (0.60) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7041150 | 0.74 | ADRB3 (0.74) | ADRB3 | |
| SCHEMBL7039442 | 0.74 | ADRB3 (0.74) | ADRB3 | |
| SCHEMBL7037348 | 0.74 | ADRB3 (0.74) | ADRB3 | |
| SCHEMBL7040072 | 0.74 | ADRB3 (0.74) | ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659737-B1 | Catecholamine surrogates useful as beta 3 agonists | BRISTOL MYERS SQUIBB CO (US) | 2003-03-26 | — | — | EP | disclosed |
| EP-0659737-A2 | Catecholamine surrogates useful as B3 agonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-06-28 | — | — | EP | disclosed |