SCHEMBL7037298

SCHEMBL7037298

C[C@H](N)C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.54
EPHX2 P34913 1/20 0.50
FABP5 Q01469 3/20 0.49
FABP7 O15540 2/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CASP3 P42574 2/20 0.44
HTR2A P28223 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17753728 1.00 KMT2A (0.54) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL30341743 0.88 KMT2A (0.49) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL768971 0.87 KMT2A (0.52) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL29823827 0.86 KMT2A (0.50) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL7391410 0.85 KMT2A (0.49) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL7389338 0.85 KMT2A (0.49) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL7393490 0.85 KMT2A (0.49) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL8236718 0.84 KMT2A (0.51) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL28758363 0.84 KMT2A (0.54) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL20623130 0.84 KMT2A (0.50) KMT2AEPHX2FABP5FABP7CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1290198-A2 VECTORS FOR DNA DELIVERY ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) 2003-03-12 EP disclosed
WO-2001088160-A2 VECTORS FOR DNA DELIVERY ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI, S.P.A. (IT) 2001-11-22 WO disclosed