Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28665432 | 0.87 | CYP1A2 (0.71) | CYP1A2CYP1A1CYP1B1CYP3A4CYP2C9 | |
| SCHEMBL11443702 | 0.87 | — | — | |
| SCHEMBL1727 | 0.87 | — | — | |
| SCHEMBL29184895 | 0.85 | CYP1A2 (0.68) | CYP1A2CYP1A1CYP1B1CYP3A4CYP2C9 | |
| Ammonia Solution, Strong SCHEMBL27802625 | 0.85 | CYP1A2 (0.68) | CYP1A2CYP1A1CYP1B1CYP3A4CYP2C9 | |
| SCHEMBL30998119 | 0.85 | CYP1A2 (0.68) | CYP1A2CYP1A1CYP1B1CYP3A4CYP2C9 | |
| Bromide SCHEMBL28157958 | 0.85 | CYP1A2 (0.68) | CYP1A2CYP1A1CYP1B1CYP3A4CYP2C9 | |
| Diethylamine SCHEMBL27925203 | 0.82 | CYP1A2 (0.54) | CYP1A2CYP1A1CYP1B1CYP3A4CYP2C9 | |
| Dimethylamine SCHEMBL28806259 | 0.80 | CYP1A2 (0.62) | CYP1A2CYP1A1CYP1B1CYP3A4CYP2C9 | |
| Bicarbonate SCHEMBL27692049 | 0.78 | CYP1A1 (0.60) | CYP1A2CYP1A1CYP1B1MAPTAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831798-B1 | USE OF SELEGILINE TO TREAT HEARING LOSS IN MAMMALS | DEPRENYL ANIMAL HEALTH INC (US) | 2003-03-19 | — | — | EP | disclosed |