Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PLEC | Q15149 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NNMT | P40261 | 1/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7041716 | 0.99 | SERPINE1 (0.54) | SERPINE1PPARGACLYKDRMAPT | |
| Lithium Ion SCHEMBL7038167 | 0.89 | PPARG (0.65) | SERPINE1PPARGKDRRXFP1ALDH1A1 | |
| SCHEMBL7034499 | 0.89 | SERPINE1 (0.52) | SERPINE1PPARGKDRMAPTRXFP1 | |
| SCHEMBL7034025 | 0.82 | KMT2A (0.59) | SERPINE1PPARGKDRMAPTALDH1A1 | |
| SCHEMBL7040328 | 0.80 | KMT2A (0.60) | SERPINE1PPARGKDRMAPTALDH1A1 | |
| SCHEMBL420125 | 0.80 | SERPINE1 (0.67) | SERPINE1PPARGKDRMAPTPLEC | |
| SCHEMBL29838623 | 0.79 | SERPINE1 (0.81) | SERPINE1PPARGKDRMAPTPLEC | |
| SCHEMBL417231 | 0.79 | SERPINE1 (0.66) | SERPINE1PPARGKDRMAPTPLEC | |
| SCHEMBL422042 | 0.79 | SERPINE1 (0.81) | SERPINE1PPARGKDRMAPTPLEC | |
| SCHEMBL420755 | 0.78 | SERPINE1 (0.80) | SERPINE1PPARGKDRMAPTPLEC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030073862-A1 | Compounds | BIOVITRUM AB (SE) | 2003-04-17 | — | — | US | disclosed |
| WO-2003004458-A1 | NEW COMPOUNDS | BIOVITRUM AB (SE) | 2003-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073862-A1 | Compounds | PPARG, PPARA, PPARD | SERPINE1 1107/4885PPARG 1/4885ACLY 451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.