Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TACR1 | P25103 | 3/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | GLI1 | P08151 | 1/20 | 0.35 |
| ▸ | GLI2 | P10070 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.34 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4702218 | 0.99 | TDP1 (0.42) | TDP1MEN1KMT2ATACR1NOS3 | |
| SCHEMBL8112100 | 0.90 | TDP1 (0.44) | TDP1MEN1KMT2ATACR1NPY1R | |
| SCHEMBL7043265 | 0.88 | TDP1 (0.42) | TDP1MEN1KMT2A | |
| SCHEMBL8612230 | 0.88 | TDP1 (0.42) | TDP1MEN1KMT2A | |
| SCHEMBL1389094 | 0.85 | TDP1 (0.38) | TDP1MEN1KMT2ANPY1RNPFFR1 | |
| SCHEMBL7750469 | 0.85 | TDP1 (0.38) | TDP1MEN1KMT2ANPY1RNPFFR1 | |
| SCHEMBL8126608 | 0.84 | TDP1 (0.41) | TDP1MEN1KMT2ANPY1RNPFFR1 | |
| Hydrochloric Acid SCHEMBL8120018 | 0.84 | TDP1 (0.37) | TDP1MEN1KMT2ANPY1RNPFFR1 | |
| SCHEMBL8119409 | 0.83 | EPOR (0.43) | TDP1MEN1KMT2ANPY1RNPFFR1 | |
| SCHEMBL1593414 | 0.83 | NPY1R (0.42) | TDP1NPY1RNPFFR1NPFFR2NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-B1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | THOMAE GMBH DR K (DE) | 2003-03-26 | — | — | EP | claimed |
| EP-0885186-B1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | THOMAE GMBH DR K (DE) | 2003-03-26 | — | — | EP | disclosed |