Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | QPCT | Q16769 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5257772 | 0.93 | SMN1; SMN2 (0.71) | MAPTCYP19A1SMN1; SMN2NPC1KMT2A | |
| SCHEMBL13177000 | 0.82 | SMN1; SMN2 (0.65) | MAPTCYP19A1SMN1; SMN2NPC1KMT2A | |
| SCHEMBL12460024 | 0.82 | SMN1; SMN2 (0.65) | MAPTCYP19A1SMN1; SMN2NPC1KMT2A | |
| SCHEMBL9999585 | 0.81 | CYP19A1 (0.67) | MAPTCYP19A1SMN1; SMN2NPC1KMT2A | |
| SCHEMBL14027226 | 0.80 | TP53 (0.72) | CYP19A1SMN1; SMN2NPC1KMT2AMAOA | |
| SCHEMBL21098369 | 0.80 | SMN1; SMN2 (0.89) | MAPTCYP19A1SMN1; SMN2NPC1KMT2A | |
| SCHEMBL10852956 | 0.79 | KMT2A (0.69) | MAPTCYP19A1SMN1; SMN2NPC1KMT2A | |
| SCHEMBL11621538 | 0.78 | MAPT (0.81) | MAPTSMN1; SMN2NPC1KMT2APOLB | |
| SCHEMBL5730977 | 0.78 | CYP19A1 (1.00) | CYP19A1KMT2AL3MBTL1 | |
| SCHEMBL17550818 | 0.78 | KMT2A (0.71) | MAPTCYP19A1SMN1; SMN2NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1052248-B1 | Process for the preparation of aqueous solutions of diazonium salts | CLARIANT GMBH (DE) | 2003-03-19 | — | — | EP | disclosed |
| US-6207809-B1 | CATALYTIC HYDROGENATION USING THE CORRESPONDING NITRO COMPOUND | CLARIANT GMBH (DE) | 2001-03-27 | — | — | US | disclosed |
| EP-1052248-A1 | Process for the preparation of aqueous solutions of diazonium salts | Clariant GmbH (DE) | 2000-11-15 | — | — | EP | disclosed |