⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromoethane SCHEMBL18911564 | 0.95 | — | — | |
| Bromoethane SCHEMBL28919542 | 0.78 | — | — | |
| Bromoethane SCHEMBL701671 | 0.74 | — | — | |
| Bromoethane SCHEMBL1331842 | 0.68 | — | — | |
| Bromoethane SCHEMBL989958 | 0.68 | — | — | |
| Bromoethane SCHEMBL2322 | 0.68 | — | — | |
| Bromoethane SCHEMBL1330309 | 0.68 | — | — | |
| N-Propyl Bromide SCHEMBL796556 | 0.67 | — | — | |
| N-Propyl Bromide SCHEMBL796355 | 0.65 | — | — | |
| N-Propyl Bromide SCHEMBL795887 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12291505-B2 | Methods for the synthesis of deuterated dextromethorphan | AVANIR PHARMACEUTICALS, INC. (US) | 2025-05-06 | — | — | US | disclosed |
| US-20240124402-A1 | METHODS FOR THE SYNTHESIS OF DEUTERATED DEXTROMETHORPHAN | AVANIR PHARMACEUTICALS INC (US) | 2024-04-18 | — | — | US | disclosed |
| US-20240067608-A1 | METHODS FOR THE SYNTHESIS OF DEUTERATED DEXTROMETHORPHAN | AVANIR PHARMACEUTICALS INC (US) | 2024-02-29 | — | — | US | disclosed |
| US-11845731-B2 | Methods for the synthesis of deuterated dextromethorphan | AVANIR PHARMACEUTICALS, INC. (US) | 2023-12-19 | — | — | US | disclosed |
| CN-106008313-B | Substituted -1,3 derovatives of isoindoline | 康塞特医药品有限公司 | 2018-11-13 | — | — | CN | disclosed |
| US-10000432-B2 | Processes for the synthesis of chiral 1-alkanols | PURDUE RESEARCH FOUNDATION (US) | 2018-06-19 | — | — | US | disclosed |
| US-20160332940-A1 | PROCESSES FOR THE SYNTHESIS OF CHIRAL 1-ALKANOLS | PURDUE RESEARCH FOUNDATION (US) | 2016-11-17 | — | — | US | disclosed |
| EP-3090999-A1 | DEUTERATED ISOINDOLINE-1, 3-DIONE DERIVATIVES AS PDE4 AND TNF-ALPHA INHIBITORS | Concert Pharmaceuticals Inc. (US) | 2016-11-09 | — | — | EP | disclosed |
| CN-106008313-A | Substituted isoindoline-1,3 dione derivatives | 康塞特医药品有限公司 | 2016-10-12 | — | — | CN | disclosed |
| US-20160264524-A1 | SUBSTITUTED ISOINDOLINE-1,3-DIONE DERIVATIVES | CONCERT PHARMACEUTICALS INC (US) | 2016-09-15 | — | — | US | disclosed |
| EP-2690092-A1 | Deuterated isoindoline-1,3-dione derivatives as PDE4 and TNF-alpha inhibitors | Concert Pharmaceuticals Inc. (US) | 2014-01-29 | — | — | EP | disclosed |
| US-20130345282-A1 | SUBSTITUTED ISOINDOLINE-1,3-DIONE DERIVATIVES | CONCERT PHARMACEUTICALS, INC. (US) | 2013-12-26 | — | — | US | disclosed |
| US-8404737-B2 | Substituted isoindoline-1,3-dione derivatives | CONCERT PHARMACEUTICALS, INC. (US) | 2013-03-26 | — | — | US | disclosed |
| US-20120252864-A1 | SUBSTITUTED ISOINDOLINE-1,3-DIONE DERIVATIVES | CONCERT PHARMACEUTICALS INC. | 2012-10-04 | — | — | US | disclosed |
| EP-2443089-A1 | DEUTERATED I SOINDOLINE- I, 3-DIONE DERIVATIVES AS PDE4 AND TNF-ALPHA INHIBITORS | Concert Pharmaceuticals Inc. (US) | 2012-04-25 | — | — | EP | disclosed |
| US-8124646-B2 | Substituted isoindoline-1,3-dione derivatives | CONCERT PHARMACEUTICALS, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-20110282587-A1 | COMPUTER READABLE STORAGE MEDIUMS, METHODS AND SYSTEMS FOR NORMALIZING CHEMICAL PROFILES IN BIOLOGICAL OR MEDICAL SAMPLES DETECTED BY MASS SPECTROMETRY | EMORY UNIVERSITY (US) | 2011-11-17 | — | — | US | disclosed |
| US-20100324108-A1 | SUBSTITUTED ISOINDOLINE-1,3-DIONE DERIVATIVES | CONCERT PHARMACEUTICALS INC. | 2010-12-23 | — | — | US | disclosed |
| WO-2010147922-A1 | DEUTERATED I SOINDOLINE- I, 3-DIONE DERIVATIVES AS PDE4 AND TNF-ALPHA INHIBITORS | CONCERT PHARMACEUTICALS, INC. (US) | 2010-12-23 | — | — | WO | disclosed |
| US-20090062298-A1 | DEUTERIUM-ENRICHED SILDENAFIL | PROTIA, LLC (US) | 2009-03-05 | — | — | US | disclosed |