SCHEMBL7038482

SCHEMBL7038482

NC(=O)c1ccnn1-c1ncccc1C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.44
GAA P10253 2/20 0.43
EPHX2 P34913 1/20 0.43
SCN9A Q15858 2/20 0.42
RBP4 P02753 1/20 0.42
CYP17A1 P05093 1/20 0.41
TRPV1 Q8NER1 6/20 0.40
SCN10A Q9Y5Y9 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15428659 0.83 SCN9A (0.42) SCN9ATRPV1SCN10A
SCHEMBL7061754 0.83 GAA (0.46) HSD11B1GAAEPHX2RBP4TRPV1
SCHEMBL7061756 0.80 KDM4E (0.49) HSD11B1GAAEPHX2SCN9ARBP4
SCHEMBL2427927 0.78 SMN1; SMN2 (0.40) SCN9ACYP17A1
SCHEMBL30097480 0.77 POLB (0.46) HSD11B1GAAEPHX2RBP4CYP17A1
SCHEMBL1570557 0.71 CTNNB1 (0.45) HSD11B1GAATRPV1NPSR1
SCHEMBL3276600 0.70 KLKB1 (0.50) HSD11B1GAAEPHX2RBP4TRPV1
SCHEMBL30861257 0.70 POLB (0.60) HSD11B1GAARBP4NPC1RAB9A
SCHEMBL27171662 0.70 POLB (0.60) HSD11B1GAARBP4NPC1RAB9A
SCHEMBL14334137 0.70 FLT3 (0.48) NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1416796-A1 METHOD FOR CONTROLLING PARTICULAR INSECT PESTS BY APPLYING ANTHRANILAMIDE COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-05-12 EP disclosed
WO-2003015518-A1 METHOD FOR CONTROLLING PARTICULAR INSECT PESTS BY APPLYING ANTHRANILAMIDE COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-02-27 WO disclosed