Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1732999 | 0.97 | CCR4 (0.81) | CCR4 | |
| SCHEMBL1733380 | 0.90 | CCR4 (0.94) | CCR4 | |
| SCHEMBL1732437 | 0.86 | CCR4 (0.76) | CCR4 | |
| SCHEMBL1732492 | 0.84 | CCR4 (1.00) | CCR4 | |
| SCHEMBL1732021 | 0.83 | CCR4 (0.90) | CCR4 | |
| SCHEMBL1733167 | 0.83 | CCR4 (1.00) | CCR4 | |
| SCHEMBL1733576 | 0.82 | CCR4 (0.70) | CCR4 | |
| SCHEMBL1731604 | 0.82 | CCR4 (0.72) | CCR4 | |
| SCHEMBL1733169 | 0.81 | CCR4 (0.71) | CCR4 | |
| SCHEMBL1732919 | 0.81 | CCR4 (0.75) | CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1467976-A1 | N-PYRAZINYL-PHENYLSULPHONAMIDES AND THEIR USE IN THE TREATMENT OF CHEMOKINE MEDIATED DISEASES | AstraZeneca AB (SE) | 2004-10-20 | — | — | EP | disclosed |
| WO-2003059893-A1 | N-PYRAZINYL-PHENYLSULPHONAMIDES AND THEIR USE IN THE TREATMENT OF CHEMOKINE MEDIATED DISEASES | ASTRAZENECA AB (SE) | 2003-07-24 | — | — | WO | disclosed |