SCHEMBL7038892

SCHEMBL7038892

O=P(O)(O)OCCC(O)Cl

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 7/20 0.40
LPAR2 Q9HBW0 5/20 0.40
LPAR1 Q92633 4/20 0.40
PGK1 P00558 1/20 0.40
PGK2 P07205 1/20 0.40
PGD P52209 3/20 0.38
MPI P34949 1/20 0.38
TPI1 P60174 1/20 0.37
LPAR5 Q9H1C0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL6030249 0.98 LPAR3 (0.39) LPAR3LPAR2LPAR1PGK1PGK2
SCHEMBL3425549 0.83 LPAR3 (0.41) LPAR3LPAR2LPAR1PGK1PGK2
SCHEMBL202466 0.80 LPAR3 (0.43) LPAR3LPAR2LPAR1PGK1PGK2
SCHEMBL27399517 0.79 LPAR3 (0.39) LPAR3LPAR2LPAR1PGK1PGK2
SCHEMBL27190160 0.78 LPAR3 (0.41) LPAR3LPAR2LPAR1PGK1PGK2
SCHEMBL11675767 0.78 LPAR3 (0.41) LPAR3LPAR2LPAR1PGK1PGK2
SCHEMBL11299607 0.77 LPAR3 (0.38) LPAR3LPAR2LPAR1PGK1PGK2
Phosphoric Acid SCHEMBL27897702 0.77 LPAR3 (0.42) LPAR3LPAR2LPAR1PGK1PGK2
SCHEMBL31506206 0.76 LPAR3 (0.45) LPAR3LPAR2LPAR1PGK1PGK2
SCHEMBL2048486 0.76 LPAR3 (0.45) LPAR3LPAR2LPAR1PGK1PGK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0820482-B1 SILICONE MODIFIED PHOSPHOLIPID COMPOSITIONS MONA INDUSTRIES INC (US) 2003-03-19 EP disclosed
EP-0820482-A4 SILICONE MODIFIED PHOSPHOLIPID COMPOSITIONS MONA INDUSTRIES INC (US) 1999-09-08 EP disclosed
US-5849313-A Silicone modified phospholipid compositions MONA INDUSTRIES, INC. (US) 1998-12-15 US disclosed
EP-0820482-A1 SILICONE MODIFIED PHOSPHOLIPID COMPOSITIONS MONA INDUSTRIES, INC. (US) 1998-01-28 EP disclosed
US-5688496-A SKIN AND HAIR CARE COSMETICS MONA INDUSTRIES, INC (US) 1997-11-18 US disclosed
WO-1996032436-A1 SILICONE MODIFIED PHOSPHOLIPID COMPOSITIONS MONA INDUSTRIES, INC. (US) 1996-10-17 WO disclosed