Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 7/20 | 0.37 |
| ▸ | PDE5A | O76074 | 5/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.30 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7042107 | 0.94 | PDE4B (0.39) | PDE4BPDE5APDE3AADORA1BMPR1B | |
| SCHEMBL7148863 | 0.87 | PDE4B (0.40) | PDE4BPDE5APDE3AADORA1 | |
| SCHEMBL7036668 | 0.87 | PDE4B (0.40) | PDE4BPDE5APDE3AADORA1 | |
| SCHEMBL7034665 | 0.86 | PDE4B (0.40) | PDE4BPDE5APDE3AADORA1 | |
| SCHEMBL7039569 | 0.86 | PDE4B (0.40) | PDE4BPDE5APDE3AADORA1 | |
| SCHEMBL7041201 | 0.86 | PDE4B (0.40) | PDE4BPDE5APDE3AADORA1 | |
| SCHEMBL7151884 | 0.84 | PDE4B (0.39) | PDE4BPDE5APDE3AADORA1 | |
| SCHEMBL7038848 | 0.81 | PDE5A (0.43) | PDE4BPDE5APDE3AADORA1 | |
| SCHEMBL7040393 | 0.80 | PDE5A (0.44) | PDE4BPDE5APDE3AADORA1 | |
| SCHEMBL7038305 | 0.78 | PDE4B (0.39) | PDE4BPDE5APDE3AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003004494-A1 | PYRIDAZINONE COMPOUND AS ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-16 | — | — | WO | disclosed |