Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7039382 | 1.00 | ADRB3 (0.81) | ADRB3 | |
| SCHEMBL7042103 | 0.89 | ADRB3 (1.00) | ADRB3 | |
| SCHEMBL7042110 | 0.89 | ADRB3 (1.00) | ADRB3 | |
| SCHEMBL7042127 | 0.89 | ADRB3 (0.78) | ADRB3 | |
| SCHEMBL7042632 | 0.85 | ADRB3 (0.72) | ADRB3 | |
| SCHEMBL7039338 | 0.85 | ADRB3 (0.72) | ADRB3 | |
| SCHEMBL7036275 | 0.85 | ADRB3 (0.72) | ADRB3 | |
| SCHEMBL27341776 | 0.78 | ADRB3 (0.58) | ADRB3 | |
| SCHEMBL7042399 | 0.77 | ADRB3 (1.00) | ADRB3 | |
| SCHEMBL7037934 | 0.77 | ADRB3 (1.00) | ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659737-B1 | Catecholamine surrogates useful as beta 3 agonists | BRISTOL MYERS SQUIBB CO (US) | 2003-03-26 | — | — | EP | claimed |
| EP-0659737-A2 | Catecholamine surrogates useful as B3 agonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-06-28 | — | — | EP | claimed |
| EP-0659737-B1 | Catecholamine surrogates useful as beta 3 agonists | BRISTOL MYERS SQUIBB CO (US) | 2003-03-26 | — | — | EP | disclosed |
| EP-0659737-A2 | Catecholamine surrogates useful as B3 agonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-06-28 | — | — | EP | disclosed |