Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 1.00 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7042049 | 1.00 | GRIA1 (1.00) | GRIA1PPARAGRIA4NPY5RCA1 | |
| SCHEMBL7109326 | 1.00 | GRIA1 (1.00) | GRIA1PPARAGRIA4NPY5RCA1 | |
| SCHEMBL24735803 | 0.91 | GRIA1 (0.83) | GRIA1PPARACA1CA2EPHX1 | |
| SCHEMBL20734509 | 0.91 | GRIA1 (0.83) | GRIA1PPARACA1CA2EPHX1 | |
| SCHEMBL13959008 | 0.91 | GRIA1 (0.83) | GRIA1PPARACA1CA2EPHX1 | |
| SCHEMBL13105698 | 0.89 | GRIA1 (0.79) | GRIA1GRIA4NPY5RKDM4EALDH1A1 | |
| SCHEMBL14654996 | 0.88 | GRIA1 (0.78) | GRIA1PPARACA1CA2EPHX1 | |
| SCHEMBL14652011 | 0.86 | GRIA1 (0.75) | GRIA1PPARAGRIA4NPY5RCA1 | |
| SCHEMBL13610004 | 0.86 | GRIA1 (0.75) | GRIA1GRIA4NPY5RCA1 | |
| SCHEMBL6754569 | 0.85 | GRIA1 (0.74) | GRIA1PPARAGRIA4CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292571-A2 | (BIS)SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2003-03-19 | — | — | EP | claimed |
| WO-2001094306-A2 | (BIS)SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-12-13 | — | — | WO | claimed |