⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640222 | 1.00 | — | — | |
| SCHEMBL20618123 | 0.79 | — | — | |
| SCHEMBL7654633 | 0.79 | — | — | |
| SCHEMBL14299387 | 0.79 | — | — | |
| SCHEMBL13428769 | 0.79 | — | — | |
| SCHEMBL24299777 | 0.79 | — | — | |
| SCHEMBL9419877 | 0.79 | — | — | |
| SCHEMBL14543908 | 0.79 | — | — | |
| SCHEMBL16446779 | 0.77 | — | — | |
| SCHEMBL29191440 | 0.77 | SMN1; SMN2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0924206-B1 | Process for producing (R)-3-Hydroxy-4-Butyrolactone useful for preparing (R)-Carnitine | SIGMA TAU IND FARMACEUTI (IT) | 2003-04-02 | — | — | EP | claimed |
| US-6127552-A | Process for producing (R)-3-hydroxy-4-butyrolactone useful for preparing (R)-carnitine | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2000-10-03 | — | — | US | claimed |
| EP-0924206-A1 | Process for producing (R)-3-Hydroxy-4-Butyrolactone useful for preparing (R)-Carnitine | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1999-06-23 | — | — | EP | claimed |
| JP-11236382-A | — | — | None | — | — | JP | disclosed |
| EP-0924206-B1 | Process for producing (R)-3-Hydroxy-4-Butyrolactone useful for preparing (R)-Carnitine | SIGMA TAU IND FARMACEUTI (IT) | 2003-04-02 | — | — | EP | disclosed |
| US-6127552-A | Process for producing (R)-3-hydroxy-4-butyrolactone useful for preparing (R)-carnitine | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2000-10-03 | — | — | US | disclosed |
| JP-H11236382-A | PRODUCTION OF (R)-3-HYDROXY-4-BUTYROLACTONE | SIGMA TAU IND FARMACEUT RIUNITE SPA | 1999-08-31 | — | — | JP | disclosed |
| EP-0924206-A1 | Process for producing (R)-3-Hydroxy-4-Butyrolactone useful for preparing (R)-Carnitine | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1999-06-23 | — | — | EP | disclosed |