Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 20/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7040709 | 1.00 | ADRB3 (0.51) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7042228 | 1.00 | ADRB3 (0.51) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7040215 | 0.92 | ADRB3 (0.61) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7040219 | 0.92 | ADRB3 (0.61) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7038384 | 0.91 | ADRB3 (0.60) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7042321 | 0.88 | ADRB3 (0.58) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7042628 | 0.88 | ADRB3 (0.57) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7042646 | 0.88 | ADRB3 (0.57) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7040721 | 0.88 | ADRB3 (0.57) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7042650 | 0.88 | ADRB3 (0.57) | ADRB3ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659737-B1 | Catecholamine surrogates useful as beta 3 agonists | BRISTOL MYERS SQUIBB CO (US) | 2003-03-26 | — | — | EP | disclosed |
| EP-0659737-A2 | Catecholamine surrogates useful as B3 agonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-06-28 | — | — | EP | disclosed |