Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | PDE8B | O95263 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17244010 | 0.95 | HSD17B10 (0.49) | HSD17B10HPGDEPHX1SMN1; SMN2NPC1 | |
| SCHEMBL1991179 | 0.87 | HSD17B10 (0.45) | HSD17B10HPGDEPHX1PREPSMN1; SMN2 | |
| SCHEMBL2896341 | 0.87 | HSD17B10 (0.45) | HSD17B10HPGDEPHX1PREPSMN1; SMN2 | |
| SCHEMBL1991177 | 0.87 | HSD17B10 (0.45) | HSD17B10HPGDEPHX1PREPSMN1; SMN2 | |
| SCHEMBL31336384 | 0.86 | HPGD (0.47) | HSD17B10HPGDEPHX1PREPSMN1; SMN2 | |
| SCHEMBL31148623 | 0.86 | HSD17B10 (0.44) | HSD17B10HPGDEPHX1PREPSMN1; SMN2 | |
| SCHEMBL17770867 | 0.86 | HSD17B10 (0.44) | HSD17B10HPGDEPHX1PREPSMN1; SMN2 | |
| SCHEMBL14398395 | 0.86 | HPGD (0.47) | HSD17B10HPGDEPHX1PREPSMN1; SMN2 | |
| SCHEMBL2689039 | 0.86 | HSD17B10 (0.44) | HSD17B10HPGDEPHX1PREPSMN1; SMN2 | |
| SCHEMBL25980668 | 0.86 | HPGD (0.47) | HSD17B10HPGDEPHX1PREPSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052497-B1 | NITROGEN CONTAINING COMPOUNDS AND THEIR USE | WOCKHARDT LTD (IN) | 2017-06-28 | — | — | EP | disclosed |
| EP-1385845-A1 | N-AROYL CYCLIC AMINES | SMITHKLINE BEECHAM PLC (GB) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002090355-A1 | N-AROYL CYCLIC AMINES | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-11-14 | — | — | WO | disclosed |