SCHEMBL7044009

SCHEMBL7044009

CC(C)(c1ccc(OC(=O)C=COC=CC(=O)O)cc1)c1ccc(OC(=O)C=COC=CC(=O)O)cc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
KMT2A Q03164 4/20 0.37
KDM4E B2RXH2 5/20 0.37
POLB P06746 1/20 0.37
RAB9A P51151 3/20 0.36
MEN1 O00255 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ALDH1A1 P00352 5/20 0.36
HTT P42858 2/20 0.36
THRB P10828 1/20 0.36
ATM Q13315 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.35
TRPV1 Q8NER1 1/20 0.35
ELANE P08246 2/20 0.35
NPC1 O15118 2/20 0.35
GAA P10253 1/20 0.34
CYP26B1 Q9NR63 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3894718 0.94 ESR1 (0.44) MAPTTDP1L3MBTL1KMT2AKDM4E
Bisphenol A SCHEMBL3894720 0.82 ESR1 (0.55) MAPTL3MBTL1KMT2AKDM4EMEN1
SCHEMBL7252916 0.81 ESR1 (0.50) MAPTTDP1L3MBTL1KMT2AKDM4E
SCHEMBL259297 0.81 ESR1 (0.50) MAPTTDP1L3MBTL1KMT2AKDM4E
SCHEMBL8349594 0.80 HIF1A (0.41) MAPTTDP1L3MBTL1KMT2AKDM4E
SCHEMBL8735250 0.78 MAPT (0.41) MAPTTDP1L3MBTL1KMT2AKDM4E
SCHEMBL10736472 0.78 SMN1; SMN2 (0.37) MAPTTDP1L3MBTL1KMT2AKDM4E
SCHEMBL29431844 0.78 SMN1; SMN2 (0.37) MAPTTDP1L3MBTL1KMT2AKDM4E
SCHEMBL28894237 0.77 MAPT (0.56) MAPTTDP1L3MBTL1KMT2AKDM4E
SCHEMBL4155998 0.77 MAPT (0.56) MAPTTDP1L3MBTL1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0796288-B1 BINDER COMPOSITION COMPRISING AMINE POLYOL REACTION PRODUCT CLARIANT FRANCE SA (FR) 2003-04-09 EP disclosed
US-5830978-A BINDERS SEQUA CHEMICALS, INC. (US) 1998-11-03 US disclosed
EP-0796288-A4 BINDER COMPOSITION COMPRISING AMINE POLYOL REACTION PRODUCT HOECHST FRANCE (FR) 1998-01-28 EP disclosed
EP-0796288-A1 BINDER COMPOSITION COMPRISING AMINE POLYOL REACTION PRODUCT SOCIETE FRANCAISE HOECHST Société anonyme dite: (FR) 1997-09-24 EP disclosed
US-5539077-A REACTION OF AMINE WITH POLYOL ALDEHYDES FOR USE AS CROSSLINKED RESIN SEQUA CHEMICALS, INC. (US) 1996-07-23 US disclosed
WO-1996017879-A1 BINDER COMPOSITION COMPRISING AMINE POLYOL REACTION PRODUCT SEQUA CHEMICALS, INC. (US) 1996-06-13 WO disclosed