Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.51 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27905861 | 0.98 | TLR8 (0.50) | TLR8GPBAR1CYSLTR1KDM4EALDH1A1 | |
| SCHEMBL22579036 | 0.90 | TLR8 (0.54) | TLR8GPBAR1CYSLTR1KDM4EALDH1A1 | |
| Phosphine SCHEMBL27716021 | 0.88 | TLR8 (0.52) | TLR8GPBAR1CYSLTR1KDM4EALDH1A1 | |
| SCHEMBL3433191 | 0.88 | TLR8 (0.55) | TLR8GPBAR1CYSLTR1KDM4EALDH1A1 | |
| SCHEMBL3634933 | 0.85 | TLR8 (0.49) | TLR8KDM4EALDH1A1GAAKMT2A | |
| SCHEMBL30952029 | 0.85 | TLR8 (0.49) | TLR8KDM4EALDH1A1GAAKMT2A | |
| SCHEMBL716117 | 0.84 | TSHR (0.50) | TLR8KDM4EALDH1A1HPGDCYP1A2 | |
| Hydrochloric Acid SCHEMBL27476977 | 0.83 | TSHR (0.49) | TLR8KDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL28700302 | 0.82 | KDM4E (0.37) | TLR8CYSLTR1KDM4EALDH1A1MEN1 | |
| SCHEMBL28691857 | 0.82 | KDM4E (0.37) | TLR8CYSLTR1KDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850280-B | 6,7-dialkyloxy-4-substituted phenylamino quinazoline compounds and preparation methods | UNIV SHAANXI NORMAL | 2015-06-10 | — | — | CN | claimed |
| CN-102850280-A | 6,7-dialkyloxy-4-substituted phenylamino quinazoline compounds and preparation methods | UNIV SHAANXI NORMAL | 2013-01-02 | — | — | CN | claimed |
| EP-0873319-A1 | QUINAZOLINE DERIVATIVES | ZENECA LIMITED (GB) | 1998-10-28 | — | — | EP | claimed |
| WO-1997022596-A1 | QUINAZOLINE DERIVATIVES | ZENECA LIMITED (GB) | 1997-06-26 | — | — | WO | claimed |
| CN-120130476-A | Application of diphenyl sulfide-containing compound in preventing and treating sunscald disease of crops | 海利尔药业集团股份有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-120130475-A | Use of biphenyl sulfide-containing compound or composition thereof for improving stress resistance of plants | 海利尔药业集团股份有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-118318839-A | Use of substituted phenylamide isoxazoline compound for controlling thysanoptera pests | 海利尔药业集团股份有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-118290356-A | Substituted benzil isoxazoline compound and application of preparation containing substituted benzil isoxazoline compound in preventing and controlling harmful mites and reducing reproductive power of harmful mites | 海利尔药业集团股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-105294716-A | Amino quinazoline derivative disalicylate and crystal form thereof | RUYUAN YAO AUTONOMOUS COUNTY DAZHONG DRUG TRADING CO LTD | 2016-02-03 | — | — | CN | disclosed |
| CN-102850280-B | 6,7-dialkyloxy-4-substituted phenylamino quinazoline compounds and preparation methods | UNIV SHAANXI NORMAL | 2015-06-10 | — | — | CN | disclosed |
| CN-102850280-A | 6,7-dialkyloxy-4-substituted phenylamino quinazoline compounds and preparation methods | UNIV SHAANXI NORMAL | 2013-01-02 | — | — | CN | disclosed |
| EP-1474420-A1 | QUINAZOLINE COMPOUNDS | Astrazeneca AB (SE) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003064413-A1 | QUINAZOLINE COMPOUNDS | ASTRAZENECA AB (SE) | 2003-08-07 | — | — | WO | disclosed |