Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 9/20 | 0.43 |
| ▸ | ESR1 | P03372 | 7/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28808638 | 0.79 | ESR2 (0.42) | ESR2ESR1DRD2DRD1TRPA1 | |
| SCHEMBL10157964 | 0.75 | BACE1 (0.38) | ESR2ESR1DRD2DRD1TRPA1 | |
| SCHEMBL17666102 | 0.74 | NPC1 (0.46) | TRPA1CYP1A2CYP2A6SRD5A1NPC1 | |
| SCHEMBL20910012 | 0.74 | ESR2 (0.35) | ESR2ESR1DRD2DRD1BACE1 | |
| SCHEMBL9770732 | 0.73 | ESR2 (0.38) | ESR2ESR1DRD2DRD1TRPA1 | |
| SCHEMBL14405270 | 0.73 | ESR2 (0.34) | ESR2ESR1DRD2DRD1TRPA1 | |
| SCHEMBL20883965 | 0.73 | ESR1 (0.39) | ESR2ESR1DRD2DRD1TRPA1 | |
| SCHEMBL30361595 | 0.73 | NPC1 (0.53) | TRPA1CYP1A2CYP2A6NPC1RAB9A | |
| SCHEMBL442330 | 0.73 | NPC1 (0.53) | TRPA1CYP1A2CYP2A6NPC1RAB9A | |
| SCHEMBL24780986 | 0.72 | PDK2 (0.41) | ESR2ESR1DRD2DRD1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030060575-A1 | Polycarbonates suitable for use in optical articles | GENERAL ELECTRIC COMPANY | 2003-03-27 | — | — | US | disclosed |