SCHEMBL7044456

SCHEMBL7044456

Cc1ccc(C)c2c1C=C(CCC1=Cc3c(C)ccc(C)c3C1[Si](C)(C)C)C2[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL690988 0.71
SCHEMBL8616027 0.66
SCHEMBL8620549 0.64
SCHEMBL8613413 0.64
Hydrochloric Acid SCHEMBL8361309 0.64
SCHEMBL8617951 0.63 SKP2 (0.31)
Hydrochloric Acid SCHEMBL7642716 0.63
Hydrochloric Acid SCHEMBL8359356 0.62
SCHEMBL7643398 0.61
Hydrochloric Acid SCHEMBL8357775 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0722950-B1 Process for the preparation of bridged metallocenes BASELL TECHNOLOGY CO BV (NL) 2001-09-12 EP claimed
US-5968863-A REACTION OF LIGAND WITH DOUBLE ANION FOR POLYMERIZATION OF OLEFINS MONTELL TECHNOLOGY COMPANY B.V. (NL) 1999-10-19 US claimed
EP-0722950-A1 Process for the preparation of bridged metallocenes Montell Technology Company bv (NL) 1996-07-24 EP claimed
EP-0819695-B1 Process for modifying the rac/meso ratio in a matallocene compound BASELL POLYOLEFINE GMBH (DE) 2003-04-09 EP disclosed
EP-0722950-B1 Process for the preparation of bridged metallocenes BASELL TECHNOLOGY CO BV (NL) 2001-09-12 EP disclosed
US-5968863-A REACTION OF LIGAND WITH DOUBLE ANION FOR POLYMERIZATION OF OLEFINS MONTELL TECHNOLOGY COMPANY B.V. (NL) 1999-10-19 US disclosed
US-5892077-A Process for modifying the rac/meso ratio in a metallocene compound MONTELL TECHNOLOGY COMPANY BV (NL) 1999-04-06 US disclosed
EP-0819695-A2 Process for modifying the rac/meso ratio in a matallocene compound Montell Technology Company bv (NL) 1998-01-21 EP disclosed
EP-0722950-A1 Process for the preparation of bridged metallocenes Montell Technology Company bv (NL) 1996-07-24 EP disclosed