Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8581724 | 0.87 | AOC3 (0.63) | AOC3ALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL31232828 | 0.83 | NPC1 (0.72) | AOC3ALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL30644009 | 0.83 | NPC1 (0.72) | AOC3ALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL4583429 | 0.82 | CYP1A2 (0.51) | AOC3ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL5065146 | 0.81 | AOC3 (0.67) | AOC3GAATDP1MTNR1AMTNR1B | |
| SCHEMBL1554809 | 0.79 | CA1 (0.58) | AOC3ALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL3649469 | 0.79 | TAAR1 (0.58) | ALDH1A1SMN1; SMN2KDM4ETDP1BCAT2 | |
| SCHEMBL9179848 | 0.79 | AOC3 (0.71) | AOC3ALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL8379013 | 0.79 | TAAR1 (0.58) | ALDH1A1SMN1; SMN2KDM4ETDP1BCAT2 | |
| SCHEMBL8379019 | 0.79 | TAAR1 (0.58) | ALDH1A1SMN1; SMN2KDM4ETDP1BCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1299103-A1 | 4,5-DIHYDRO-THIAZO-2-YLAMINE DERIVATIVES AND THEIR USE AS NO-SYNTHASE INHIBITORS | Aventis Pharma S.A. (FR) | 2003-04-09 | — | — | EP | disclosed |
| WO-2001093867-A1 | 4,5-DIHYDRO-THIAZO-2-YLAMINE DERIVATIVES AND THEIR USE AS NO-SYNTHASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2001-12-13 | — | — | WO | disclosed |