Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 1/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.44 |
| ▸ | MMP9 | P14780 | 4/20 | 0.40 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3918256 | 1.00 | PTGFR (0.58) | PTGFRHSD11B1MMP9MMP2CA12 | |
| SCHEMBL3383657 | 0.91 | PTGFR (0.59) | PTGFRHSD11B1MMP9MMP2MMP1 | |
| SCHEMBL13005135 | 0.91 | PTGFR (0.58) | PTGFRHSD11B1MMP9MMP2MMP1 | |
| SCHEMBL7047521 | 0.91 | PTGFR (0.58) | PTGFRHSD11B1MMP9MMP2MMP1 | |
| SCHEMBL3383792 | 0.91 | PTGFR (0.58) | PTGFRHSD11B1MMP9MMP2MMP1 | |
| SCHEMBL3384306 | 0.89 | PTGFR (0.56) | PTGFRHSD11B1MMP9MMP2CA12 | |
| SCHEMBL3381583 | 0.89 | PTGFR (0.54) | PTGFRHSD11B1MMP9MMP2CA12 | |
| SCHEMBL3382557 | 0.88 | PTGFR (0.64) | PTGFRHSD11B1MMP9MMP2CA12 | |
| SCHEMBL3382579 | 0.88 | PTGFR (0.64) | PTGFRHSD11B1MMP9MMP2CA12 | |
| SCHEMBL3382653 | 0.88 | PTGFR (0.64) | PTGFRHSD11B1MMP9MMP2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487442-A1 | THIAZOLIDINE CARBOXAMIDE DERIVATIVES AS MODULATORS OF THE PROSTAGLANDIN F RECEPTOR | Applied Research Systems ARS Holding N.V. (AN) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003082278-A1 | THIAZOLIDINE CARBOXAMIDE DERIVATIVES AS MODULATORS OF THE PROSTAGLANDIN F RECEPTOR | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-10-09 | — | — | WO | disclosed |