SCHEMBL704528

SCHEMBL704528

COc1c([C@@H](C)N(C)C(=O)c2nn(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)c2CC(=O)O)ccc(F)c1Cl

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL700493 0.90 CNR1 (0.51) CNR1
SCHEMBL703178 0.85 CNR1 (0.51) CNR1
SCHEMBL703177 0.80 CNR1 (0.59) CNR1
SCHEMBL27782788 0.80 CNR1 (0.59) CNR1
SCHEMBL700492 0.80 CNR1 (0.62) CNR1
SCHEMBL702210 0.79 CNR1 (0.49) CNR1
SCHEMBL704527 0.79 CNR1 (0.51) CNR1
SCHEMBL2679126 0.75 CNR1 (0.65) CNR1
SCHEMBL15435698 0.74 CNR1 (0.54) CNR1
SCHEMBL701834 0.73 CNR1 (0.41) CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2121617-B1 CB1 RECEPTOR MODULATORS 7TM PHARMA AS (DK) 2014-01-22 EP disclosed
US-8124634-B2 CB1 receptor modulators 7TM PHARMA A/S (DK) 2012-02-28 US disclosed
US-20100010061-A1 CB1 RECEPTOR MODULATORS 7TM PHARMA A/S (DK) 2010-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100010061-A1 CB1 RECEPTOR MODULATORS CNR1, CNR2, GPR6 CNR1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.