Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7048092 | 0.88 | CYP3A4 (0.51) | CYP3A4USP2MAPK1SMN1; SMN2HPGD | |
| SCHEMBL347816 | 0.88 | KDM4E (0.47) | CYP3A4USP2MAPK1SMN1; SMN2HPGD | |
| SCHEMBL7050534 | 0.84 | CYP3A4 (0.42) | CYP3A4USP2MAPK1SMN1; SMN2HPGD | |
| SCHEMBL16290680 | 0.83 | CYP3A4 (0.46) | CYP3A4USP2MAPK1SMN1; SMN2HPGD | |
| SCHEMBL2865673 | 0.82 | CYP3A4 (0.54) | CYP3A4MAPK1HPGDKDM4EMAPT | |
| Methyl 2,4,6-Trimethoxybenzoate SCHEMBL2563067 | 0.81 | CYP3A4 (0.58) | CYP3A4USP2MAPK1SMN1; SMN2HPGD | |
| SCHEMBL3831737 | 0.81 | HSD17B10 (0.45) | CYP3A4USP2MAPK1SMN1; SMN2HPGD | |
| SCHEMBL6501990 | 0.81 | CYP3A4 (0.51) | CYP3A4USP2MAPK1SMN1; SMN2HPGD | |
| SCHEMBL16246149 | 0.79 | HSD17B10 (0.44) | CYP3A4USP2MAPK1SMN1; SMN2HPGD | |
| SCHEMBL16993027 | 0.79 | HSD17B10 (0.44) | CYP3A4USP2MAPK1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1300403-A1 | Process for the manufacture of hypoxyxylerone derivatives | Aventis Pharma S.A. (FR) | 2003-04-09 | — | — | EP | disclosed |