SCHEMBL7045574

SCHEMBL7045574

CCN(CCCOS(=O)(=O)O)c1cccc(C)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 1/20 0.48
▸ CYP3A4 P08684 1/20 0.48
▸ CYP2D6 P10635 1/20 0.48
▸ CYP2C19 P33261 1/20 0.48
▸ HTT P42858 3/20 0.45
▸ TP53 P04637 2/20 0.45
▸ ALDH1A1 P00352 6/20 0.45
▸ KMT2A Q03164 3/20 0.45
▸ MEN1 O00255 2/20 0.45
▸ MAPT P10636 6/20 0.44
▸ LMNA P02545 4/20 0.44
▸ USP2 O75604 2/20 0.44
▸ GFER P55789 5/20 0.43
▸ HPGD P15428 4/20 0.43
▸ NPSR1 Q6W5P4 2/20 0.43
▸ GAA P10253 2/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ SMN1; SMN2 Q16637 3/20 0.43
▸ TSHR P16473 2/20 0.43
▸ TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9872251 0.92 CYP3A4 (0.45) CYP1A2CYP3A4CYP2D6CYP2C19HTT
SCHEMBL9873109 0.85 RECQL (0.41) CYP1A2CYP3A4CYP2D6CYP2C19HTT
SCHEMBL9649906 0.84 CYP1A2 (0.46) CYP1A2CYP3A4CYP2D6CYP2C19HTT
SCHEMBL11696065 0.83 GFER (0.47) CYP1A2CYP3A4CYP2D6CYP2C19HTT
SCHEMBL186733 0.82 CYP1A2 (0.51) CYP1A2CYP3A4CYP2D6CYP2C19HTT
SCHEMBL29387582 0.82 CYP1A2 (0.51) CYP1A2CYP3A4CYP2D6CYP2C19HTT
SCHEMBL30848155 0.81 CYP1A2 (0.50) CYP1A2CYP3A4CYP2D6CYP2C19HTT
SCHEMBL5525904 0.81 CYP1A2 (0.50) CYP1A2CYP3A4CYP2D6CYP2C19HTT
SCHEMBL1592182 0.81 CYP1A2 (0.50) CYP1A2CYP3A4CYP2D6CYP2C19HTT
SCHEMBL11692794 0.80 GFER (0.46) CYP1A2CYP3A4CYP2D6CYP2C19HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5755231-A Test strip including integral specimen flow retarding structure PLUS BIO, INC. (US) 1998-05-26 — — US claimed
WO-1998000703-A1 TEST STRIP INCLUDING INTEGRAL SPECIMEN FLOW RETARDING STRUCTURE PLUS BIO, INC. (US) 1998-01-08 — — WO claimed
US-5156954-A Hydrogen peroxide generated by reaction of analyte in the presence of oxidase converts substrate reagent to colored reaction product CHOLESTECH CORPORATION (US) 1992-10-20 — — US claimed
EP-0806671-B1 Automated urinalysis system for detecting blood in urine CHIMERA RES AND CHEMICAL INC (US) 2003-04-16 — — EP disclosed
EP-0539495-B1 DEVICE AND METHOD FOR MEASURING HDL-CHOLESTEROL EMPLOYING PRECIPITATION ON A SOLID-PHASE CHOLESTECH CORP (US) 2001-01-17 — — EP disclosed
EP-1028319-A2 Device and method for measuring HDL-cholesterol emplying precipitation on a solid-phase CHOLESTECH CORPORATION (US) 2000-08-16 — — EP disclosed
US-5755231-A Test strip including integral specimen flow retarding structure PLUS BIO, INC. (US) 1998-05-26 — — US disclosed
US-5733785-A QUANTITATIVE ANALYSIS CHINERA RESEARCH CHEMICAL, INC. (US) 1998-03-31 — — US disclosed
WO-1998000703-A1 TEST STRIP INCLUDING INTEGRAL SPECIMEN FLOW RETARDING STRUCTURE PLUS BIO, INC. (US) 1998-01-08 — — WO disclosed
EP-0806671-A1 Automated urinalysis system for detecting blood in urine Chimera Research and Chemical, Inc. (US) 1997-11-12 — — EP disclosed
US-5516700-A Automated urinalysis method CHIMERA RESEARCH AND CHEMICAL, INC. (US) 1996-05-14 — — US disclosed
US-5451370-A Analysis for cholesterol and lipoproteins with fiber pads for blood, glass fibers and reservoirs CHOLESTECH CORPORATION (US) 1995-09-19 — — US disclosed
US-5213965-A Measuring high density lipoprotein concentration CHOLESTECH CORPORATION (US) 1993-05-25 — — US disclosed
US-5213964-A Separation from low density lipoproteins using glass fiber filter treated with polyvinyl alcohol or an aminosilane CHOLESTECH CORPORATION (US) 1993-05-25 — — US disclosed
EP-0539495-A1 SOLID-PHASE PRECIPITATION ASSAY DEVICE AND METHOD CHOLESTECH CORPORATION (US) 1993-05-05 — — EP disclosed
US-5156954-A Hydrogen peroxide generated by reaction of analyte in the presence of oxidase converts substrate reagent to colored reaction product CHOLESTECH CORPORATION (US) 1992-10-20 — — US disclosed
WO-1992001498-A2 SOLID-PHASE PRECIPITATION ASSAY DEVICE AND METHOD CHOLESTECH CORPORATION (US) 1992-02-06 — — WO disclosed
WO-1990002200-A1 SELF-CORRECTED ASSAY DEVICE AND METHOD CHOLESTECH CORPORATION (US) 1990-03-08 — — WO disclosed
EP-0357400-A2 Self-corrected assay device and method CHOLESTECH CORPORATION (US) 1990-03-07 — — EP disclosed
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