Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 15/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.59 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.38 |
| ▸ | PFKFB2 | O60825 | 1/20 | 0.38 |
| ▸ | PFKFB1 | P16118 | 1/20 | 0.38 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6083485 | 1.00 | SLC6A4 (0.59) | SLC6A4SLC6A2SLC6A3IMPDH2IMPDH1 | |
| SCHEMBL6083489 | 1.00 | SLC6A4 (0.59) | SLC6A4SLC6A2SLC6A3IMPDH2IMPDH1 | |
| SCHEMBL6083497 | 1.00 | SLC6A4 (0.59) | SLC6A4SLC6A2SLC6A3IMPDH2IMPDH1 | |
| SCHEMBL6085855 | 0.84 | SLC6A4 (0.58) | SLC6A4SLC6A2SLC6A3PFKFB2PFKFB1 | |
| SCHEMBL6085863 | 0.84 | SLC6A4 (0.58) | SLC6A4SLC6A2SLC6A3PFKFB2PFKFB1 | |
| SCHEMBL6085857 | 0.84 | SLC6A4 (0.58) | SLC6A4SLC6A2SLC6A3PFKFB2PFKFB1 | |
| SCHEMBL6083852 | 0.83 | SLC6A4 (0.59) | SLC6A4SLC6A2SLC6A3PFKFB2PFKFB1 | |
| SCHEMBL6083828 | 0.81 | SLC6A4 (0.57) | SLC6A4SLC6A2SLC6A3PFKFB2PFKFB1 | |
| SCHEMBL6083831 | 0.81 | SLC6A4 (0.57) | SLC6A4SLC6A2SLC6A3PFKFB2PFKFB1 | |
| SCHEMBL6084783 | 0.81 | SLC6A4 (0.62) | SLC6A4SLC6A2SLC6A3IMPDH2IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026237-A2 | COMPOUNDS FOR THE TREATMENT OF PREMATURE EJACULATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-04-01 | — | — | WO | disclosed |