Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 20/20 | 0.61 |
| ▸ | SRC | P12931 | 10/20 | 0.61 |
| ▸ | TEK | Q02763 | 8/20 | 0.61 |
| ▸ | FYN | P06241 | 3/20 | 0.48 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.47 |
| ▸ | PLK4 | O00444 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | PAK4 | O96013 | 1/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | INSR | P06213 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | LYN | P07948 | 1/20 | 0.47 |
| ▸ | HCK | P08631 | 1/20 | 0.47 |
| ▸ | FGR | P09769 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4826428 | 0.92 | LCK (0.65) | LCKSRCTEKFYNLIMK1 | |
| SCHEMBL4826559 | 0.90 | LCK (0.63) | LCKSRCTEKFYNLIMK1 | |
| SCHEMBL4821436 | 0.86 | LCK (0.80) | LCKSRCTEKFYNLIMK1 | |
| SCHEMBL5823953 | 0.84 | LCK (0.69) | LCKSRCTEKFYNLIMK1 | |
| SCHEMBL6218794 | 0.83 | LCK (0.69) | LCKSRCTEKFYNLIMK1 | |
| SCHEMBL6278841 | 0.83 | LCK (0.69) | LCKSRCTEKFYNLIMK1 | |
| Acetic Acid SCHEMBL4828254 | 0.81 | LCK (0.67) | LCKSRCTEKFYNLIMK1 | |
| SCHEMBL4820493 | 0.81 | LCK (0.68) | LCKSRCTEKFYNLIMK1 | |
| SCHEMBL7050233 | 0.81 | LCK (0.66) | LCKSRCTEKFYNLIMK1 | |
| Acetic Acid SCHEMBL6245563 | 0.80 | LCK (0.66) | LCKSRCTEKFYNLIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004100868-A2 | METHOD OF TREATING TRANSPLANT REJECTION | ABBOTT LABORATORIES (US) | 2004-11-25 | — | — | WO | disclosed |