Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 10/20 | 0.48 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31359160 | 0.83 | ERN1 (0.52) | ERN1TRIM24TRIM33MEN1NPC1 | |
| SCHEMBL27657430 | 0.83 | ERN1 (0.52) | ERN1TRIM24TRIM33MEN1NPC1 | |
| SCHEMBL31300223 | 0.80 | ERN1 (0.54) | ERN1TRIM24TRIM33TDP1MEN1 | |
| SCHEMBL4617412 | 0.80 | ERN1 (0.54) | ERN1TRIM24TRIM33MEN1NPC1 | |
| SCHEMBL219677 | 0.80 | ERN1 (0.54) | ERN1TRIM24TRIM33TDP1MEN1 | |
| SCHEMBL1982095 | 0.78 | ERN1 (0.52) | ERN1TRIM24TRIM33TDP1MEN1 | |
| SCHEMBL29915579 | 0.78 | ERN1 (0.52) | ERN1TRIM24TRIM33TDP1MEN1 | |
| SCHEMBL3842233 | 0.78 | TDP1 (0.45) | ERN1TRIM24TRIM33TDP1MEN1 | |
| Hydrochloric Acid SCHEMBL29595412 | 0.77 | ERN1 (0.50) | ERN1TRIM24TRIM33TDP1MEN1 | |
| SCHEMBL15195884 | 0.77 | ERN1 (0.50) | ERN1TRIM24TRIM33MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004110351-A2 | HETEROCYCLIC COMPOUNDS FOR TREATING HEPATITIS C VIRUS | ANADYS PHARMACEUTICALS, INC. (US) | 2004-12-23 | — | — | WO | disclosed |