Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622341 | 1.00 | CYP2C19 (0.61) | CYP2C19LMNAKMT2AMMP2MMP3 | |
| SCHEMBL8749863 | 1.00 | CYP2C19 (0.61) | CYP2C19LMNAKMT2AMMP2MMP3 | |
| SCHEMBL8838995 | 0.96 | CYP2C19 (0.62) | CYP2C19LMNAKMT2AMMP2MMP3 | |
| SCHEMBL7799794 | 0.96 | CYP2C19 (0.62) | CYP2C19LMNAKMT2AMMP2MMP3 | |
| SCHEMBL9507072 | 0.91 | CYP2C19 (0.65) | CYP2C19LMNAKMT2AMMP2MMP3 | |
| SCHEMBL7776762 | 0.90 | CYP2C19 (0.62) | CYP2C19LMNAKMT2AMMP2MMP3 | |
| SCHEMBL7775183 | 0.88 | CYP2C19 (0.51) | CYP2C19LMNAKMT2AMMP2MMP9 | |
| SCHEMBL9621846 | 0.87 | CYP2C19 (0.55) | CYP2C19LMNAKMT2AMMP2MMP3 | |
| SCHEMBL7773269 | 0.87 | CYP2C19 (0.50) | CYP2C19LMNAKMT2ACYP1A2TSHR | |
| SCHEMBL7776791 | 0.84 | CYP2C19 (0.52) | CYP2C19LMNAKMT2AMMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784795-B1 | POST SYNTHESIS CHEMICAL MODIFICATION OF PARTICLE REAGENTS | DADE BEHRING INC (US) | 2003-04-02 | — | — | EP | disclosed |
| US-5854083-A | Post synthesis chemical modification of particle reagents | DADE BEHRING INC. (US) | 1998-12-29 | — | — | US | disclosed |
| CN-1166205-A | Post synthesis chemical modification of particle reagents | DADE CHEMISTRY SYSTEMS INC (US) | 1997-11-26 | — | — | CN | disclosed |
| EP-0784795-A1 | POST SYNTHESIS CHEMICAL MODIFICATION OF PARTICLE REAGENTS | Dade Chemistry Systems Inc. (US) | 1997-07-23 | — | — | EP | disclosed |
| WO-1997006438-A1 | POST SYNTHESIS CHEMICAL MODIFICATION OF PARTICLE REAGENTS | DADE CHEMISTRY SYSTEMS INC. (US) | 1997-02-20 | — | — | WO | disclosed |
| US-4244939-A | RADIOIMMUNOASSAY | BAXTER TRAVENOL LABORATORIES, INC. (US) | 1981-01-13 | — | — | US | disclosed |