Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HMGCR | P04035 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7046254 | 1.00 | GRIK1 (0.39) | GRIK1EGLN1TSHRKDM4ERECQL | |
| SCHEMBL7121339 | 0.86 | GRIK1 (0.38) | GRIK1TSHRKDM4ERECQLLDHA | |
| SCHEMBL25245418 | 0.82 | GRIK1 (0.36) | GRIK1TSHRKDM4ERECQLALDH1A1 | |
| SCHEMBL14280076 | 0.80 | GRIK1 (0.52) | GRIK1TSHRKDM4ERECQLTET2 | |
| SCHEMBL12373465 | 0.78 | EGLN1 (0.43) | GRIK1EGLN1TSHRKDM4ERECQL | |
| SCHEMBL15741484 | 0.74 | TSHR (0.60) | EGLN1TSHRKDM4ERECQLTET2 | |
| SCHEMBL2926536 | 0.74 | TSHR (0.60) | EGLN1TSHRKDM4ERECQLTET2 | |
| SCHEMBL2926538 | 0.74 | TSHR (0.60) | EGLN1TSHRKDM4ERECQLTET2 | |
| SCHEMBL12101265 | 0.74 | EGLN1 (0.40) | EGLN1TSHRKDM4ERECQLTET2 | |
| SCHEMBL3146499 | 0.73 | POLB (0.41) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042270-B1 | ASYMMETRIC HYDROGENATION | CHIROTECH TECHNOLOGY LTD (GB) | 2003-04-09 | — | — | EP | disclosed |
| US-6207853-B1 | SUCCINIC ACID DERIVATIVE | CHIROTECH TECHNOLOGY, INC. (GB) | 2001-03-27 | — | — | US | disclosed |
| EP-1042270-A1 | ASYMMETRIC HYDROGENATION | Chirotech Technology Limited (GB) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999031041-A1 | ASYMMETRIC HYDROGENATION | CHIROTECH TECHNOLOGY LIMITED (GB) | 1999-06-24 | — | — | WO | disclosed |