Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 16/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7044217 | 0.91 | CNR1 (0.57) | CNR1NPC1RAB9ACNR2 | |
| SCHEMBL6552432 | 0.90 | CNR1 (0.57) | CNR1NPC1RAB9ACNR2 | |
| SCHEMBL7045579 | 0.90 | CNR1 (0.57) | CNR1NPC1RAB9ACNR2 | |
| SCHEMBL7041065 | 0.89 | CNR1 (0.52) | CNR1CNR2 | |
| SCHEMBL7046412 | 0.87 | CNR1 (0.46) | CNR1CNR2 | |
| SCHEMBL7041796 | 0.85 | CNR1 (0.43) | CNR1NPC1RAB9ACNR2 | |
| SCHEMBL7044571 | 0.83 | CNR1 (0.55) | CNR1CNR2 | |
| SCHEMBL7043527 | 0.83 | CNR1 (0.44) | CNR1CNR2 | |
| SCHEMBL6081479 | 0.82 | CNR1 (0.52) | CNR1CNR2 | |
| SCHEMBL7043337 | 0.82 | CNR1 (0.56) | CNR1NPC1RAB9ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | claimed |