Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 18/20 | 0.60 |
| ▸ | PPARG | P37231 | 17/20 | 0.60 |
| ▸ | PPARA | Q07869 | 17/20 | 0.60 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.58 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7046234 | 0.91 | PPARD (0.62) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL7044850 | 0.91 | PPARA (0.69) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL7039142 | 0.90 | PPARA (0.75) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL8003777 | 0.88 | PPARG (0.76) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL7041413 | 0.86 | PPARD (0.81) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL7037984 | 0.83 | PPARA (0.59) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL7041349 | 0.83 | PPARD (0.70) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL6559207 | 0.82 | PPARG (0.58) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL6559245 | 0.81 | PPARA (0.75) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL7041575 | 0.80 | PPARG (0.72) | PPARDPPARGPPARANR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882029-B1 | HETEROCYCLIC DERIVATIVES AS ANTIDIABETIC AND ANTIOBESITY AGENTS | MERCK & CO INC (US) | 2003-04-02 | — | — | EP | claimed |