Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 19/20 | 0.79 |
| ▸ | PPARG | P37231 | 16/20 | 0.79 |
| ▸ | PPARA | Q07869 | 16/20 | 0.79 |
| ▸ | NR1H2 | P55055 | 9/20 | 0.63 |
| ▸ | NR1H3 | Q13133 | 9/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7040035 | 0.89 | PPARD (0.85) | PPARDPPARGPPARANR1H2NR1H3 | |
| L-165461 SCHEMBL6753428 | 0.89 | PPARD (1.00) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL7039659 | 0.88 | PPARD (0.86) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL7044857 | 0.85 | PPARD (0.78) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL7038966 | 0.84 | PPARD (0.92) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL7042204 | 0.82 | PPARA (0.73) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL7046133 | 0.81 | PPARA (0.74) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL7040439 | 0.80 | PPARD (0.71) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL23139545 | 0.80 | PPARD (0.84) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL5535084 | 0.80 | PPARD (0.83) | PPARDPPARGPPARANR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882029-B1 | HETEROCYCLIC DERIVATIVES AS ANTIDIABETIC AND ANTIOBESITY AGENTS | MERCK & CO INC (US) | 2003-04-02 | — | — | EP | claimed |